Dr. Stephania Cormier

Wiener Chair ProfessorStephania Cormier
BMB/CDIB  Division

Honorary Professor Child Health , University of Queensland, Australia
Honors BS - Biology and Chemistry, 1991, University of Louisiana
PhD - Biochemistry and Molecular Biology, 1997
Louisiana State University Medical Center
Fellowship: Pulmonary and Critical Care Medicine, Mayo Clinic Scottsdale, AZ

Office Phone: 225-578-9437 (ORED) / 225-763-2691 (PBRC)
Lab Phone: 225-578-9762 (PBRC)
Lab: PBRC
Office: L1016 PBRC / ORED 130 D. Boyd
E-mail: stephaniacormier@lsu.edu 

Area of Interest

Respiratory Immunology & Toxicology

The main goal of my laboratory is to determine if exposure during early life to environmental factors (i.e. allergens, pollutants, and respiratory viruses) leads to predisposition, development of, or exacerbation of respiratory disease in the adult. We believe that adult respiratory diseases result, in part, from environmental impacts that occur during a critical phase of immuno-maturation. In the short term, we seek:

  1. to define the cellular and molecular changes in the pulmonary microenvironment following gestational and/or neonatal exposure
  2. to determine if urban pollutants (e.g. particulates such as diesel exhaust particles), initiate cellular/molecular events in the developing lung which lead to increased susceptibility to airways disease later in life
  3. to define the impact of respiratory viral infection on pulmonary pathophysiology of the infant; and
  4. to understand how urban pollutants impact host defense resulting in enhanced morbidity and increased mortality from respiratory infections

The long-term objective of my laboratory is to realize the initiators of the immune and pathophysiological changes that occur during the early stages of pulmonary airways disease and ultimately to develop effective interventions and therapies.  

Selected Publications

Complete list of publications

Environmental Impacts on COVID-19: Mechanisms of Increased Susceptibili
SA Cormier, A Yamamoto, KR Short, L Vu, WA Suk
Annals of Global Health 88 (1)

Genomic Basis for Individual Differences in Susceptibility to the Neurotoxic Effects of Diesel Exhaust 
A Noël, DG Ashbrook, F Xu, SA Cormier, L Lu, JP O’Callaghan, ...
International Journal of Molecular Sciences 23 (20), 12461

Beyond the Unknown: A Broad Framing for Preparedness for Emerging Infectious Threats
RC Christofferson, SA Cormier
The American Journal of Tropical Medicine and Hygiene, tpmd220341-tpmd220341

Metal-Free Biomass-Derived Environmentally Persistent Free Radicals (Bio-EPFRs) from Lignin Pyrolysis 
L Khachatryan, M Barekati-Goudarzi, R Asatryan, A Ozarowski, D Boldor, ...
ACS omega 7 (34), 30241-30249

Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis 
J Liu, S Li, X Fei, X Nan, Y Shen, H Xiu, SA Cormier, C Lu, C Guo, S Wang, ...
Autophagy 18 (5), 971-989

IL-1β Promotes Expansion of IL-33+ Lung Epithelial Stem Cells after Respiratory Syncytial Virus Infection during Infancy 
LD Vu, ATQ Phan, DR Hijano, DT Siefker, H Tillman, SA Cormier
American Journal of Respiratory Cell and Molecular Biology 66 (3), 312-322

IL-1β Promotes Expansion of IL-33+ Lung Epithelial Stem Cells Following RSV Infection During Infancy. 
LD Vu, ATQ Phan, DR Hijano, DT Siefker, H Tillman, SA Cormier
American Journal of Respiratory Cell and Molecular Biology

The interplay between environmental exposures and COVID-19 risks in the health of children
PD Sly, BA Trottier, CM Bulka, SA Cormier, J Fobil, RC Fry, KW Kim, ...
Environmental Health 20 (1), 1-10

Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production 
A Kumar, VS Patel, JN Harding, D You, SA Cormier
Particle and Fibre Toxicology 18 (1), 1-11

Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17 
JN Harding, M Gross, V Patel, S Potter, SA Cormier
Respiratory Research 22 (1), 1-16

Age Dependent Reduction of Neutralization Capacities Against Delta Variant Five Months Post-Vaccination (BNT162b2) 
LD VU, S Wallace, A Phan, RC Christofferson, E Turner, S Parker, ...

Reduced turnaround times through multi-sectoral community collaboration during the first surge of SARS-CoV-2 and associated effect on patient care and hospital operations 
RC Christofferson, HR O’Neal, T Jagneaux, C O’Neal, CS Walsh, ...
Plos one 16 (10), e0257302

Particulate matter exposure predicts residence in high-risk areas for community acquired pneumonia among hospitalized children 
TJ Oyana, J Minso, TL Jones, JA McCullers, SR Arnold, SA Cormier
Experimental Biology and Medicine 246 (17), 1907-1916

Integrative Cardiovascular Physiology and Pathophysiology: Deficiency in ST2 signaling ameliorates RSV-associated pulmonary hypertension 
LD Vu, J Saravia, S Jaligama, RVB Panday, RD Sullivan, S Mancarella, ...
American Journal of Physiology-Heart and Circulatory Physiology 321 (2), H309

Deficiency in ST2 signaling ameliorates RSV-associated pulmonary hypertension 
LD Vu, J Saravia, S Jaligama, RV Baboeram Panday, RD Sullivan, ...
American Journal of Physiology-Heart and Circulatory Physiology 321 (2 …

The Effect of Combustion Generated Environmentally Persistent Free Radicals on Well-Differentiated Human Airway Epithelial Cells 
A Yamamoto, AJ Yeo, PD Sly, SA Cormier, S Lomnicki, L Khachatryan, ...
TP109. TP109 COPD AND E-CIGARETTES: PRE-CLINICAL MODELS AND MECHANISMS …

EFFECT OF ENVIRONMENTALLY PERSISTENT FREE RADICALS ON HUMAN AIRWAY EPITHELIUM
A Yamamoto, A Yeo, P Sly, S Cormier, L Khachatryan, F Hasan, E Fantino
RESPIROLOGY 26, 142-142

Developmental Hazard of Environmentally Persistent Free Radicals and Protective Effect of TEMPOL in Zebrafish Model 
X Guan, L Truong, S M. Lomnicki, R L. Tanguay, S A. Cormier
Toxics 9 (1), 12

Combustion by-products and their health effects: Summary of the 16th international congress 
A Violi, S Cormier, B Gullett, S Jansson, S Lomnicki, C Luyet, A Mayer, ...
Fuel 283, 118562

more publications