Philip William West Lectureship in Analytical Chemistry

Dr. West profile

Professor Philip W. West (1913-2001)
 

Professor West was LSU’s first Boyd Professor of Chemistry, the highest professorial rank awarded at LSU. Dr. West received his Ph.D. in 1939 from the University of Iowa, joined the LSU faculty in 1940, and retired in 1980. During his career, Professor West published over 180 scientific articles and three books in the field of water treatment and analysis, polarized light microscopy, air pollution, chromatography, industrial hygiene, and personal monitors. Dr. West earned national science awards, including three from the American Chemical Society: the Southwest Award, the Fisher Award, and the Award for Creative Advances in Environmental Science and Technology. Dr. West was a devoted educator, researcher, and entrepreneur. He founded a private company, the West-Paine Laboratories, and directed the LSU Symposium on Modern Methods of Analytical Chemistry, which brought essentially all the well-known names in analytical chemistry to the LSU campus between 1948 and 1965.

The West Lectureship in Analytical Chemistry is held once each academic year at Louisiana State University and is given by an internationally known scientist who is performing research in Analytical Chemistry. The West Lectureship speaker is selected by graduate students pursuing analytical chemistry research, and the visit is organized and coordinated by a committee of graduate students, with help and guidance from a Faculty committee.

Two talks are given. First a general talk, aimed at the broader LSU and Baton Rouge community. The second talk is more technical, appropriate for a chemistry audience. 

2020 West Lectureship: TBA

Dr. Wysocki portrait

Vicki Wysocki, Ph.D.
Ohio Eminent Scholar
Department of Chemistry and Biochemistry
The Ohio State University

Wysocki Research Group

Session 1
 
Title: "Team Science Tackles Salmonella Infection"
 
Abstract: TBA

 
 
 
Session 2
 
Title: "New Approaches to Protein Structure Characterization by Mass Spectrometry"
 
Abstract: Characterization of the overall topology and inter-subunit contacts of protein complexes, and their assembly/disassembly and unfolding pathways, is critical because protein complexes regulate key biological processes, including processes important in understanding and controlling disease. Tools to address structural biology problems continue to improve. Native mass spectrometry (nMS) and associated technologies such as ion mobility are becoming an increasingly important component of the structural biology toolbox. When the mass spectrometry approach is used early or mid-course in a structural characterization project, it can provide answers quickly using small sample amounts and samples that are not fully purified. Integration of sample preparation/purification with effective dissociation methods (e.g., surface-induced dissociation), ion mobility, and computational approaches provide a MS workflow that can be enabling in biochemical, synthetic biology, and systems biology approaches. Native MS can determine whether the complex of interest exists in a single or in multiple oligomeric states and can provide characterization of topology/intersubunit connectivity, and other structural features. Beyond its strengths as a stand-alone tool, nMS can also guide and/or be integrated with other structural biology approaches such as SEC, SAXS, AUC, NMR, X-ray crystallography, and cryoEM. We have recently improved SID designs and installed SID in multiple instrument platforms. Examples will be presented to illustrate complementary data provided by native MS/SID and other structural biology tools.
 

Previous West Lectureship Speakers:  

Dr. Heineman  
January 18-19, 2019
William R. Heineman, Ph.D.
Distinguished Research Professor Emeritus
University of Cincinnati

Title: “Spectroelectrochemical Sensors: The Quest for Selectivity”

Abstract: Exceptional selectivity is needed for sensors to accurately measure analytes in complex samples such as nuclear waste and natural water that contain many potentially interfering substances. Spectroelectrochemistry offers a unique means for providing selectivity without resorting to fragile biochemicals used for biosensors. A novel sensor that combines electrochemistry, spectroscopy, and selective partitioning in a single device has been developed. The analyte is first preconcentrated from the sample solution into a very thin film that also rejects some sample components. An additional level of selectivity is provided by subjecting the preconcentrated analyte to electrolysis at an underlying optically transparent electrode, which electrochemically modulates the optical signal that is used for quantitation. The modulated signal can then be distinguished from the constant signals of potential interferences. The sensor works with both visible absorption and fluorescence modes of detection. Sensors have been developed for ferrocyanide and technetium complexes in nuclear waste and natural water, polycyclic aromatic hydrocarbons, ferrous and ferric iron, and heavy metals such as lead, cadmium and mercury.

 

Dr. Wirth
July 20, 2016
Mary J. Wirth, Ph.D.
Purdue University
W. Brooks Fortune Distinguished Professor – Analytical Chemistry

 

 

Dr. Zare profile
December 15-16, 2014
Richard N. Zare, Ph.D.
Stanford University
Marguerite Blake Wilbur Professor in Natural Science and Professor, by courtesy, of Physics
 

Title: “Mass Spectrometry: Drop by Drop” 

 

Dr. Armstrong

January 30-31, 2014
Daniel W. Armstrong, Ph.D. 
The University of Texas at Arlington 
Robert A. Welch Distinguished Professor
 

 

Title: “Performance Enhancing Drugs: Background, Detection & Incidents”

Abstract: The use of performance enhancing drugs (PED) has a long history in sports and combat, and only in the last several decades has become an area of concern. This is because issues of health, safety and fairness have come to the forefront. Further, the regulation and control of these substances and those who would use them is an effective way for large regulation-based organizations to acquire power, funds, etc. Also the use of PEDs has extended from world-class athletes and military uses to recreational sports and other venues. A brief history of PEDs will be given, along with an overview of their types and effects. Finally we will take a specific look at a recently banned stimulant that was a constituent of one of the largest selling nutritional supplements in the world. 

 

Dr. Kennedy profile
October 25-26, 2012
Robert T. Kennedy, Ph.D.
University of Michigan
Hobart Willard Distinguished University Professor
Professor of Chemistry, College of Literature, Science, and the Arts
Professor of Pharmacology, Medical School
Professor of Macromolecular Science & Engineering, College of Engineering

Title: "Chemistry of the Mind"